Monday, 4th August
2014 International Biophysics Congress
Days
Sunday, 3rd August
Monday, 4th August
Tuesday, 5th August
Wednesday, 6th August
Thursday, 7th August
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Speakers
Engstrom Lecture
9:00AM - 10:00AM
Monday, 4th August
Great Hall - enter doors 7 and 8
Chair: Daniela Stock
Serial femtosecond nanocrystallography opens anew avenues for structural biology
-
Petra Fromme
Morning Tea
10:00AM - 10:30AM
Monday, 4th August
Great Hall Mezzanine Foyer
S1. Membrane protein assemblies
10:30AM - 12:30PM
Monday, 4th August
Great Hall - enter doors 7 and 8
Chair: Kazuhiko Kinosita, Jr.
co-Chair: Megan Maher
CryoEM image analysis of macromolecular motor assemblies
-
Keiichi Namba
Cryo-ET of large mitochondrial protein complexes
-
Karen Davies
Structural dissection of architecture of caveolar protein coat
-
Oleksiy Kovtun
Mechanistic insight into mitofusin-mediated membrane fusion
-
Xiaoyu Hu
Edge detection and segmentation of organelles, membranes and macromolecular complexes
-
Ben Hankamer
S2. Protein structure to function - 1
10:30AM - 12:30PM
Monday, 4th August
M4
Chairs: Igor Berezovsky & Ray Norton
Dissecting oncogenic RAS signaling by NMR
-
Mitsu Ikura
Examining the allosteric properties of key metabolic enzymes
-
Emily Parker
Targeting of a natural killer cell receptor family by a viral immunoevasin
-
Richard Berry
Ligand interactions and dynamics of a malaria protein that plays a key role in erythrocyte invasion
-
Raymond S. Norton
S3. Dynamic fluorescence imaging
10:30AM - 12:30PM
Monday, 4th August
M3
Chairs: Michelle Digman & Elvis Pandzic
Chromatin structure and dynamics
-
Enrico Gratton
Single-molecule studies of DNA replication: From
in vitro
to
in vivo
-
Antoine M. van Oijen
A single-molecule view on kinesin motor-protein cooperation in intraflagellar transport in living
C. elegans
-
Erwin J.G. Peterman
Imaging the diffusive route of transcription factor activity in live cells by fluctuation analysis
-
Elizabeth Hinde
Solvent relaxation in Golgi membrane by Phasor-FLIM approach
-
Alireza Lajevardipour
Molecular tools for targeted covalent labeling and light-induced activation of biopolymers
-
Saulius Klimasauskas
S4. Visualizing molecules of life
10:30AM - 12:30PM
Monday, 4th August
M2
Chairs: Bonnie Ann Wallace & Boris Martinac
Structural studies of the gating mechanism in a pentameric ligand-gated ion channel
-
Marc Delarue
Visualizing GPCRs at the single molecule level to reveal subtleties of signaling mechanisms
-
Anthony Watts
New paradigms in GPCR organization and dynamics
-
Amitabha Chattopadhyay
Conformational dynamics of a G protein coupled receptor at the single-molecule level
-
David P. Millar
Label-free optical detection and super-resolution imaging of single proteins
-
Marek Piliarik
S5. Bioenergetics systems: The cellular context
10:30AM - 12:30PM
Monday, 4th August
M1
Chairs: Galina Riznichenko & Ron Clarke
A structural systems-biology approach to cell biology by electron microscopy: Multiscale structural analysis from bulk tissue to the full proteome of a single cell
-
Henning Stahlberg
CryoEM and CryoET studies of protein structure and dynamics
-
Steven Ludtke
Gating in channelrhodopsin
-
Joachim Heberle
Interrelationship between H
2
cycling and proton motive force generation in
Escherichia coli
during glycerol fermentation
-
Karen Trchounian
Lunch
12:30PM - 1:00PM
Monday, 4th August
Great Hall Mezzanine Foyer
IUPAB Executive Meeting
12:45PM - 2:00PM
Monday, 4th August
M5
Please note this is a closed meeting
Poster Session 1
1:00PM - 2:30PM
Monday, 4th August
Great Hall Mezzanine Foyer
Determination of relations between hemarehology, lipid peroxidation, antioxidant defence and trace elements in COPD
-
Mehmet Can Akyolcu
Incorporation of amphiphilic cyclodextrins in biomimetic lipid assemblies
-
Angelina Angelova
Eumelanin as a bioelectronic material
-
Shermiyah Baguisa
Unraveling a network of interactions involved in the trafficking of virulence proteins in
P. falciparum
-infected erythrocytes
-
Steven Batinovic
Biophysical changes facilitate cellular invasion during metastasis: An
in vitro
model
-
Shalmoli Bhattacharyya
Mechanisms of infrared stimulation of auditory neurons
in vitro
-
William G.A. Brown
Analysis of the hydration water around bovine serum albumin using terahertz coherent synchrotron radiation
-
Robert J. Falconer
Characterization of fusion between mammalian tumor cells and mouse sperm
-
Qiang Chen
Vesicles, queues and insulin-responsive glucose trafficking
-
Adelle C.F. Coster
Artificial polymer brush film mimics the physiological and rheological behaviors of bronchial epithelial cilium
-
Linhong Deng
Study on changes of coagulation factors activity in different periods of pregnancy
-
Xu Hairong
Probing the membrane-inserted form of CLIC1 using fluorescence spectroscopy
-
Joanna E. Hare
Senescence of long-term G2 arrested melanoma cells
-
Jinpeng He
Herpes simplex virus capsid protein encoding genes
UL18
and
UL19
: A promising antiviral targets for RNA interfernce-based therapeutic approach
-
Fujun Jin
Effect of glycosidic linkage on the sugar specificity of Jacalin
-
Abhinav K.V.
Targeting double stranded RNA with spermine and 1-naphthyl acetyl spermine: A comparative biophysical investigation
-
Ayesha Kabir
In situ
structures of
Salmonella
injectisome and flagellar type III secretion systems by electron cryotomography
-
Akihiro Kawamoto
A particle dynamics model of cell-cell rotation and morphological behavior
-
Fong Yew Leong
Magnetic resonance biomarkers of altered lipid metabolism during liver cancer development
-
Sami Alghamdi
The intracellular architectures of filopdoia were observed by cryo-ET at molecular resolution
-
Shinji Aramaki
Utility of F-18 fluorodeoxyglucose PET-CT in the management of Iodine-131 scan negative thyroid cancer with raised thyroglobulin
-
Anish Bhattacharya
A multimodal approach to the study of magnetic nanoparticles interaction with breast cancer cells
-
Jose L. Carrascosa
Nano-scale spatial-temporal dynamics of paxillin and actin in 3D collagen matrices
-
Michelle Digman
Characterization of CEACAM1 structure and dynamics by correlated homo-FRET and dSTORM imaging
-
Amine Driouchi
Phase change nanoemulsions for cancer therapy and imaging
-
Donald A. Fernandes
Microfluidic isolation of protein complexes from cell lysates for visual analysis by quantitative electron microscopy
-
Dominic Giss
Xinjiang Uygur herbs image feature extraction and discriminant analysis based on color and textural feature
-
Murat Hamit
Abnormal Savda Munziq, a formulation of Uighur medicine ameliorates memory impairment by improves cholinergic system an alleviates oxidative stress in the Tg-APPswe/PS1dE9 mouse model of Alzheimer’s disease
-
Nurmuhammat Amat
Charge at the 46
th
residue of Cx50 is critical for the gap junctional unitary conductance and transjunctional voltage-dependent gating
-
Donglin Bai
An experimental validation of calculated liquid junction potentials for monovalent ion solutions and problems that can arise with solution mixtures of different ion valencies
-
Peter H. Barry
Choline activates and modulates low-sensitivity α
4
β
2
neuronal nicotinic acetylcholine receptors
-
Ladislas Bizimana
The origins of ion selectivity in a bacterial sodium channel revealed by µs-long simulations
-
Celine Boiteux
The γ subunit of Na
+
,K
+
-ATPase, FXYD2, is involved in inflammatory pain
-
Bing Cai
Brain iron accumulation exacerbates the pathogenesis of MPTP-induced Parkinson's disease
-
Yan-Zhong Chang
Age-dependent expression of duodenal cytochrome B561, divalent metal transporter 1 and ferroportin 1 in duodenum of rats
-
Yan-Zhong Chang
Potent and specific blockers of ASIC1a with potential for treatment of stroke
-
Irene Chassagnon
Multiple ligand-binding fine-tunes TRPV1 response to the pungent stimulant capsaicin
-
Huai-hu Chuang
A new target for the alpha-conotoxins: The GABA(B) receptor
-
Richard J. Clark
The analgesic sea anemone peptide APETx2 interacts with both ASIC3 and hERG via overlapping pharmacophores
-
Ben Cristofori-Armstrong
The GABA
A
receptor γ1 subunit influences inhibitory synaptic currents via receptor clustering
-
Christine L. Dixon
Local sequence of protein ß-strands influences twist and bend angles
-
Kazuo Fujiwara
Inhibitory effects of angiotensin II on BK
Ca
channels in podocytes via oxidative stress
-
Na Gao
Voltage-dependent block of cardiac sodium channels expressed in Xenopus oocytes by bupivacaine
-
Yonghua Ji
Potential action of low intensity ultrasound on iGluRs and AQP4 membrane localization to inhibit brain edema formation in rats
-
Mrigendra Bir Karmacharya
Unsaturated fatty acids drastically accelerate the channel opening of voltage-gated proton channel
-
Akira Kawanabe
Peptides derived from the transmembrane domain of Bcl-2 proteins as potential mitochondrial priming tools
-
Mibel Aguilar
The effect of exogenous melatonin on the salinity-induced noise in salt-sensitive
Characeae Chara australis
-
Sabah Al Khazaaly
Permeability and mechanism of transport of cisplatin across lipid membranes
-
Nasma Almansouri
Membrane permeabilization induced by sphingosine: Effect of negatively-charged lipids
-
Alicia Alonso
Protein-induced millisecond structural transitions in lipid membrane nanoparticles
-
Angelina Angelova
Role of a unique arginine residue on the assembly of the translocator domain in a trimeric autotransporter
-
Eriko Aoki
Structure prediction of GPCRs using piecewise homologs and application to the human CCR5 chemokine receptor: Validation through agonist and antagonist docking
-
Karthik Arumugam
Exploring curvature
in-vitro
on
in-vivo
lengthscales
-
Hanna M.G. Barriga
Functional and structural characterization of PlyC-B at lipid membrane interface
-
Marilia Barros
Molecular mechanism for atlastin-mediated homotypic fusion of endoplasmic reticulum membranes
-
Xin Bian
VCA1008: A new anion-selective trimeric porin of
vibrio cholerae
-
Paulo Mascarello Bisch
A method to gain insight into the functioning of Colicin A
-
Ana Bouchet
Triggering dynamic structural changes in model lipid membranes using pressure jump technology
-
Nick J. Brooks
How does isoprene protect plants from heat stress? Investigation using model lipid membranes
-
Gary Bryant
Probing the interaction dynamics between a model antimicrobial peptide and giant unilamellar vesicles
-
Matthew G. Burton
The interface between the transport and the trimerisation domains of a human glutamate transporter mediates chloride permeation
-
Rosemary J. Cater
Effect of Mg
2+
ions on the Na
+
/K
+
-ATPase conformation
-
Petra Cechova
Pair-wave heterodyning SPR study of amyloid beta molecule interaction with membrane mimic of raft constituency
-
Wei Ju Chen
Structural and biophysical studies of the e. Coli Mechanosensitive channel of large conductance
-
Gamma Chi
A novel 'outward-occluded' conformation of an antibacterial peptide ABC transporter
-
Hassanul G. Choudhury
Lipid-protein interplay in the mechanism of the sodium pump
-
Ronald J. Clarke
Computer-aided drug discovery: development of a method for G protein-coupled receptor binding pocket refinement
-
Thomas Coudrat
Membrane induced structure of novel human tachykinin hemokinin-1 (hHK1)
-
Sudha Cowsik
Nano-scale ion sequestration using tethered lipid bilayers to determine the polarity selectivity of ion channel conductance
-
Charles G. Cranfield
Arf1 induced membrane remodeling and morphological changes studied by cryoEM, confocal microscopy and Langmuir film balance
-
Sebastian Daum
Attempting homology modeling, energy optimization and structural validation of a difficult target SERAC1: The protein involved in an inborn error of metabolism, MEGDEL syndrome
-
Surajit Debnath
Targeting multidrug resistance in breast cancer: Structural and functional investigation of BCRP
-
Chandrika Deshpande
Functional and structural characterisation of the L-type amino acid transporters
-
Josep Font Sadurni
Transporters of the multidrug resistance: Reconstitution into proteoliposomes and biophysical characterisation
-
Hans-Joachim Galla
Biophysical investigations of the structure and function of the meibomian lipid films and the effect of ectoine
-
Hans-Joachim Galla
Comparison of solute profile of simple sugars between lamellar stacks of dioleoylphosphatidylcholine by neutron membrane diffraction
-
Christopher J. Garvey
Reactivity of cysteins on the large cytoplasmic segment (C45) of Na+/K+-ATPase
-
Jaroslava Geleticova
Capsaicin disorders and fluidifies DPPC model membranes
-
Juan C. Gomez-Fernandez
Quartz crystal microbalance with dissipation monitoring of dynamic viscoelastic changes of tobacco BY-2 cells under different osmotic conditions
-
Zongxing Chen
Spectroscopic studies of the super relaxed state of skeletal muscle
-
Roger Cooke
sADAM33
modulation alters mechanical behaviors of airway smooth muscle cells through phenotype transition
-
Linhong Deng
Excessive TGFβ signaling and matrix metalloproteinases activity contributes to genetic thoracic aortopathy
-
Candice L Dilworth
Activation of nicotinic receptor channels guides keratinocyte migration toward acetylcholine (ACh) gradient in the direct current (DC) electric field
-
Sergei Grando
Mechanism of electricity-mediated change of cellular uptake and intracellular trafficking
-
Kentaro Kogure
Interaction of triplex forming oligonucleotide with a promoter region of
hmga1
and its anti-cancer activity associated with decreased HMGA1 expression
-
Md. Zahid Akhter
Disorder and (dis)orientation
-
Jane R. Allison
Protein nanoparticle bioconjugate: BSAn-Emodin, structure-function and in vivo toxicity
-
Silvia del V Alonso
Structural characterisation of conotoxin Geo3330 by 2D-NMR
-
David A. Armstrong
Peptide-based isolation of circulating tumor cells by magnetic nanoparticles
-
Linling Bai
Fullerenol 16(OH) inhibits Aβ
1-40
amyloid aggregation
-
Zuzana Bednarikova
Mechanisms of allosteric regulation and communication
-
Igor N. Berezovsky
Structure and interactions of dok1 PTB domain with b2 cytosolic tail of integrin
-
Surajit Bhattacharyya
A novel antiviral therapeutic target: The Vacuolar Protein Sorting 4 AAA-ATPase
-
Lou Brillault
Critical role of TLRs and MicroRNAs in radiation-induced carcinogenesis
-
Jianming Cai
Crystal structure of enterovirus 71 RNA-dependent RNA polymerase complexed with its protein primer VPg: Implication for a trans mechanism of VPg uridylylation
-
Cheng Chen
Crystallization, preliminary X-Ray crystallographic and Cryo-electron microscopy analysis of a bifunctional enzyme fucokinase/L-fucose-1-P-guanylyltransferase from B.
Fragilis
-
Chongyun Cheng
Manifestations of molecular self-organization in single molecule reactions
-
Leonid N. Christophorov
Solution structure of a phytocystatin from
Sesamum indicum
and its intermolecular interaction with cysteine proteases
-
Chia-Lin Chyan
Structural studies to elucidate the catalytic mechanism of Diaminopropionate ammonia lyase
-
Geeta Deka
The residues V210 and F224 is the key interaction sites between δ-COP and its sorting motif and the structure analysis of δ-COP C-terminal domain
-
Kai Deng
Crystal structure of the Rab9A-RUTBC2 complex reveals the binding specificity of Rab9 with its effectors
-
Jianping Ding
Role of calcium binding in
T. gondii
glideosome
-
Marta Enciso
Phosphorylation of cardiac calsequestrin enhance its interaction with junctin
-
Xuexin Fan
Imidazolium-based ionic liquids as triggers of lysozyme amyloid fibrillization
-
Diana Fedunova
Functional studies of 16S rRNA methyltransferase RsmF from
Thermus thermophilus
using transcriptomic and proteomic techniques
-
Jingyuan Feng
Comparison of heme degradation patterns during interaction of hemoglobin with n-alkyl sulfates
-
Leila Fotouhi
Structural diversity of a novel family of cyclic plant peptides
-
Bastian Franke
Role of the flexibility of antigen binding site in high affinity antibody elucidated by surface plasmon resonance
-
Natsuki Fukuda
The artificial assembly of the bacterial flagellar motor switch complex
-
Lorraine Ganuelas
Design of novel gp41-based immunogens for HIV-1 vaccine development
-
Guofen Gao
Differential cytotoxic effect in response to polymorphism of amyloid fibrils
-
Zuzana Gazova
Crystal structure of Rot, a global regulator of virulence genes in
Staphylococcus aureus
-
Yuwei Zhu
Coupling scheme of the rotary motor thermophilic F
1
-
Kengo Adachi
Millisecond time-resolved small-angle X-ray scattering revealing the kinetic pathways of lipid membrane complexes formation with DNA and proteins
-
Angelina Angelova
DNA aptamers as theranostic tools to detect and regulate apoptosis
-
Md Ashrafuzzaman
Single-molecule enzymology with ClyA nanopores
-
Annemie Biesemans
Double-strand DNA-templated copper nanoparticles as electrochemical probes for glutathione detection
-
Ya Cao
Smart Droplet Microtools: An optically controlled platform for single-cell sampling and payload delivery
-
Duncan Casey
Biodegradable DNA nanoparticles for efficient
in vivo
thymulin gene delivery in experimental chronic allergic inflammation
-
Adriana L. da Silva
Temperature dependence of DNA hairpin disorder: Effects of adsorption onto gold
-
Kurt L.M. Drew
Application to protein structure stabilization of fragment obtained from FBDD approach
-
Kei Fukushima
Flavonolignans and their antioxidant properties
-
Michal Biler
In
silico
studies of enzimes from indole-3-acetic acid metabolic pathways in the endophytic bacterium
gluconacetobacter diazotrophicus
-
Paulo Mascarello Bisch
Describing space-temporal patterns produced by a bistable switch in developmental gene regulatory network
-
Paulo Mascarello Bisch
In silico single-molecule manipulation of DNA with rigid body dynamics
-
Bertrand Caré
Molecular dynamics investigations of protein barrel flexibility and oxygen diffusion pathways in the red fluorescent protein mCherry
-
Prem Chapagain
Based on structural and pseudo-amino acid composition information to predict the anti- and pro-apoptosis proteins
-
Yingli Chen
Is flexibility P-glycoprotein's superpower?
-
Karmen Condic-Jurkic
How protein ligands affect the conformation of the erythropoietin receptor dimer
-
Michael Corbett
Is more information always better? What type of experimentally-derived restraints are most effective in the docking of a ligand: Protein complex
-
Evelyne Deplazes
Magnetoferritin nanoparticles for cancer diagnosis
-
Kelong Fan
The emptied bacteriophage T4 capsid: A novel nanoparticle vehicle to efficiently deliver genes into the body
-
Guofen Gao
A switching hydrogen bond explains the bathochromic shifts observed in mPlum
-
Bernard Gerstman
Computational approaches for inhibition of mammalian tyrosinase
-
Sangwon Jung
Effects of calmodulin on calcium activation of cardiac ryanodine receptor
-
Ye Win Oo
Probing the role of spatial anisotropy and heterogeneity in contractility and adhesion distribution during cell steering
-
Soumya S S
A systematic muscle model simulating the fast ramp stretches in the muscle fibres
-
Youjiro Tamura
ABCB1-overexpressing MDCK-II cells are hypersensitive to 3-bromopyruvic acid
-
Izabela Sadowska-Bartosz
Studies on electrical hysteresis in Gorgon nut
-
Mohammed Sye
Simultaneous and efficient introduction of multiple µm-sized objects into live cells by a novel cell-GUV electrofusion technique
-
Akira C: Saito
Self gravitation bio: Some convincing evidences on astrophysical principles
-
Iresh Ranjan Bhattacharjee
Study on the Relationship between Histone Modifications and Gene Expression Levels in the Human H1 cell line
-
Qian-Zhong Li
Stabilizing the open state of Kv4.2 by BmP02
-
Bin Wu
Influences of native energetic heterogeneity and many-body interaction in φ value analysis of protein folding
-
Zhuqing Zhang
Plenary Lecture 1
2:30PM - 3:30PM
Monday, 4th August
Great Hall - enter doors 7 and 8
Chair: Frances Separovic
Molecular insights into the regulation of T cell signalling with single molecule localisation microscopy
-
Katharina Gaus
Afternoon Tea
3:30PM - 4:00PM
Monday, 4th August
Great Hall Mezzanine Foyer
S6. Receptors and signalling
4:00PM - 6:00PM
Monday, 4th August
Great Hall - enter doors 7 and 8
Chairs: Karmen Condic-Jurkic & Jacqueline Gulbis
Cell-free synthesis and crystallographic structural analyses of integral membrane proteins
-
Shigeyuki Yokoyama
Crystal structure determination of the integral membrane diacylglycerol kinase
-
David Aragao
Insulin's interaction with its receptor - a complex choreography of conformational change
-
Mike C. Lawrence
N-Glycosylation determines structural arrangement of Epidermal Growth Factor Receptor on a membrane
-
Karol Kaszuba
Interactions of Dok7 with anionic lipid bilayers studied by multiscale MD simulation
-
Amanda Buyan
S7. Emerging imaging technologies
4:00PM - 6:00PM
Monday, 4th August
M4
Chairs: Tatyana Smirnova & Patrick Cozzone
Protein structure determination using nano crystals and MicroED
-
Tamir Gonen
X-ray Free-Electron Lasers – a bright future for structural biology
-
Ilme Schlichting
Label-free imaging using intrinsic photonic signatures
-
Shan Shan Kou
Nanodiamonds as fluorescent quantum probes in biology
-
Lloyd C.L. Hollenberg
S8. Neuroscience - 1
4:00PM - 6:00PM
Monday, 4th August
M3
Chairs: Arie Moran & Marcus Wilson
Activity-dependent neural plasticity from bench to bedside
-
Muming Poo
pH modulation of neuronal excitability involves a pyramidal cell axon initial segment NaV1.2 channel specific mechanism
-
Steven Petrou
Channelrhodopsin et al.: Photoreceptors for optogenetic applications
-
Georg Nagel
Neurobiophysics of excitotoxicity of IgGs and mSOD1 as humoral factors of amyotrophic lateral sclerosis pathophysiology
-
Pavle R. Andjus
Structural and functional studies of the a4b2 nAChRs using wild-type and engineered acetylcholine binding proteins as structural surrogates
-
Thomas Balle
S9. Skeletal and smooth muscle Ca2+ signalling
4:00PM - 6:00PM
Monday, 4th August
M2
Chairs: Roger Cooke & Angela Dulhunty
The puzzling phenotype of calsequestrin-1 knockout mice: What have we learned?
-
Feliciano Protasi
Triadin and junctin – their role in regulating skeletal muscle calcium release
-
Nicole Beard
Ca
2+
uptake by the tubular (t-) system of skeletal muscle fibres
-
Bradley S. Launikonis
Comparison of simulated calcium sparks and calcium sparks recorded in intact amphibian skeletal muscle
-
Janos Vincze
Controlling vascular contractile responses with novel small molecule inhibitors of zipper-interacting protein kinase
-
Justin A. MacDonald
S10. Biomolecular simulation
4:00PM - 6:00PM
Monday, 4th August
M1
Chairs: Prem Chapagain & Alan Mark
Challenges in bio-molecular research: On comparing simulated with experimental data
-
Wilfred F. van Gunsteren
Bacterial models as tools for sodium channel mechanistic discovery
-
Toby W. Allen
Elucidation of catalytically competent protonation states of key residues in glycoside hydrolases
-
Haibo Yu
Hamiltonian replica-permutation method and its application to Aβ fragments
-
Satoru G. Itoh
Designing hydrophobic gates into biomimetic nanopores
-
Jemma L. Trick
Japanese Bid Function
6:00PM - 7:00PM
Monday, 4th August
M2
Please note this is a closed function
IUPAB Council Meeting
2:00PM - 4:00PM
Monday, 4th August
M5
Please note this is a closed meeting
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