Xiyun Yan 2014 International Biophysics Congress

Xiyun Yan

Professor / Director, key Laboratory of Protein & Peptide Pharmaceutical, Institute of Biophysics, Chinese Academy of Sciences; Vice President & Secretary-General, Biophysical Society of China E-mail: yanxy@sun5.ibp.ac.cn Education and Work Experience: 1997- present Professor, Selected for 100 Talents Program, Chinese Academy of Sciences 1994-1996 Post-doc, Immunology, Memorial Sloan-Kettering Cancer Center, U.S.A 1989-1993 M.D., Microbiology and Immunology, Heidelberg University, Germany Research Interests: 1. Her team made groundbreaking contribution to our knowledge of nanozyme that Fe3O4 nanoparticles having an intrinsic peroxidase-like activity (Nature Nanotechnology, 2007), which open a promising field towards the development of nanozyme. Based on this finding, they developed several new technologies for tumor diagnosis and therapy (Nature Nanotechnology, 2012) as well as detection and treatment of phenolic wastewater. 2. She discovered that CD146 is a biomarker for angiogenesis and plays a key role in tumor metastasis (Blood,2003), illustrated the mechanism of CD146 in angiogenesis (Nature Communication 2014, Blood 2012, PNAS 2012) and developed a therapeutic humanized antibody targeting CD146, which has been in pre-clinical trial to treat tumors.

Abstracts this author is presenting: