Oral Presentation 2014 International Biophysics Congress

Imaging the Dynamic Mechanisms Forming the Mammalian Embryo (#198)

Nicolas Plachta 1
  1. Monash University, Clayton, VIC, Australia

My lab has recently designed new imaging tools to study how mammalian cells chose their fate and interactions with neighbouring cells during the earliest stages of embryonic development. We have shown how gene-regulatory transcription factors find their DNA targets to control cell identity, and how cells change their shape and position to form some of the first tissue-like structures of the developing mouse embryo. Our findings reveal some of the dynamic mechanisms controlling key cell functions in living mammalian organisms.