Poster Presentation 2014 International Biophysics Congress

Rapid noncontact photoacoustic tomography imaging using an interferometer with phase modulation technique (#569)

Zhilie Tang 1 , Yongbobo Wu 1 , Jun Liu 1 , Hongchun Tang 1 , Yi Wang 1
  1. South China Normal University, Guangzhou, China

For biological imaging, we designed, fabricated, and tested a system of rapid noncontact photoacoustic tomography (PAT) imaging using a low-coherence interferometer with phase modulation technique. To improve the practicability of the system, a rapid noncontact probing technique was applied. This technique is experimentally verified by capturing images of a simulated tissue sample and the blood vessels within the ear flap of a mouse (pinna) in vivo. The axial and lateral resolutions of the system are evaluated at 45 and ~15 μm, respectively. The imaging depth of the system is 1 mm in a special phantom. Study results show that the system can be used in PAT imaging and that it realizes the possibility of noncontact, real-time PAT.